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Co-Trimoxazole should not be used in pregnancy, particularly in the first trimester, unless clearly necessary. Folate supplementation should be considered if Co-Trimoxazole is used in pregnancy. Sulfamethoxazole competes with bilirubin for binding to plasma albumin. As significantly maternally derived drug levels persist for several days in the.
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Co-trimoxazole is a well tolerated, off-patent, low-cost, and effective treatment for various bacterial and parasitic diseases endemic in developing countries. However, this meta-analysis poses more questions than answers for the issues it purported to answer. Specifically designed studies are urgently needed to define safe and effective.
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1. What Co-Trimoxazole is and what it is used for Co-Trimoxazole 16 mg/80 mg per ml for Infusion (called 'Co-Trimoxazole' in this leaflet) is a combination of two different antibiotics called sulfamethoxazole and trimethoprim, which is used to treat infections caused by certain bacteria. Like all antibiotics, Co-Trimoxazole only works against
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Cotrimoxazole is one much miracle drug having broad antibacterial spectrum making it suitable for use in a wide variety of infections and the good tissue penetration makes it useful for the treatment of infections involving multiple systems of the body. For instance, the rate of resistance to cotrimoxazole in the year 2012 in our hospital was.
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Introduction Cotrimoxazole (CTX) has been used for half a century. It is inexpensive hence the reason for its almost universal availability and wide clinical spectrum of use. In the last decade, CTX was used for prophylaxis of opportunistic infections in HIV infected people. It also had an impact on the malaria risk in this specific group. Objective We performed a systematic review to explore.
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redness, swelling, or soreness of the tongue. seizures. soreness of the muscles. stiff neck or back. stomach tenderness. swelling of the face, hands, legs, and feet. unsteadiness, trembling, or other problems with muscle control or coordination. weakness in the hands or feet. weakness or heaviness of the legs.
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The invention relates to a preparation for reducing the side effect of cotrimoxazole and a preparation method thereof. The critical components of the preparation include sulfamethoxazole (SMZ), trimethoprim (TMP), beta-cyclodextrin, sodium bicarbonate, starch and magnesium stearate. The preparation comprises, by mass, 3.6 to 13.5% of sulfamethoxazole (SMZ), 0.7 to 4.5% of trimethoprim (TMP), 3.
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Co-trimoxazole injection is used to treat certain infections that are caused by bacteria such as infection of the intestine, lungs (pneumonia), and urinary tract. Co-trimoxazole should not be used in children younger than 2 months of age. Co-trimoxazole injection is in a class of medications called sulfonamides. It works by killing bacteria.
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There were 232 infants with congenital anomalies among 4196 women receiving cotrimoxazole during pregnancy, giving an overall pooled prevalence of 3.5% (95% CI 1.8-5.1%; τ 2 0.03). Three studies reported 31 infants with neural tube defects, giving a crude prevalence of 0.7% (95%CI 0.5-1.0%) with most data (29 neural tube defects) coming.
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Co-trimoxazole is a combination antibiotic. It can be taken by people who are allergic to penicillin, but it is not suitable for people who are allergic to sulfonamides. Space out your doses evenly throughout the day, and remember to finish the course of treatment. The most common side-effects are feeling sick, diarrhoea and headache.
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Cotrimoxazole is a combination of two antimicrobial drugs (sulfamethoxazole and trimethoprim) that is a broad spectrum antimicrobial agent targeting a variety of aerobic Gram-positive and Gram-negative organisms and protozoa. Therefore, it is of particular interest for prophylactic treatment, since it has a broad coverage against common.
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V. F. has a patent pending in sepsis diagnostics, "Biomarkers for the molecular classification of bacterial infection". Patent application no. US 14/214,853. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been.
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Trimethoprim-sulfamethoxazole (TMP-SMX), also known as co-trimoxazole, is a combination of two antimicrobial agents that act synergistically against a wide variety of bacteria. Although other combinations of sulfonamides are available with trimethoprim, TMP-SMX is by far the most widely used. This topic will review basic issues related to the.
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Understand key drug designations in just a few clicks with Synapse. SPY-001: a α4β7 antagonists Drug, Initially developed by Spyre Therapeutics, Inc., Now, its global highest R&D status is Preclinical, Mechanism: α4β7 antagonists (Integrin alpha-4/beta-7 antagonists), Therapeutic Areas: Digestive System Disorders, Active Indication.
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Ciclosporin — patients who have received a kidney transplant and are receiving co-trimoxazole and ciclosporin concomitantly are at an increased risk of having a reversible deterioration in their kidney function. Spironolactone — concurrent use can increase the likelihood of hyperkalemia, especially in the elderly. The trimethoprim portion.
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Co-trimoxazole is used to treat certain bacterial infections, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the urinary tract, ears, and intestines. It also is used to treat 'travelers' diarrhea. Co-trimoxazole is a combination of trimethoprim and sulfamethoxazole and is in a.